Report
Questions put to test in evidence-based analysis of aspartame research
A just-published research review concludes that, media speculation aside, using aspartame as a sweetener has no effect on appetite or food intake. The same evaluation reaffirmed what regulators and health authorities have said many times before: aspartame is not associated with adverse effects for the population at large.
“The conclusions shouldn’t be a surprise to health professionals, as they reflect what science and common sense have told us for years,” said Brendan Naulty, president of Ajinomoto North America. “Aspartame is a safe and potentially valuable tool for helping consumers manage their calories.”
The evaluation, posted on the ADA Evidence Analysis Library website, answers several recently raised questions concerning aspartame. For example:
- Some have claimed that low-calorie sweeteners like aspartame could have a ‘rebound’ effect that leads people to have more of an appetite or to eat more food. The analysis found: “There is good evidence that aspartame does not affect appetite or food intake”. This consensus statement was given a ‘grade 1′, the highest grade in the EAL scale.
- Others have implied, despite the implausibility, that low-calorie sweeteners actually ‘make’ people gain weight. The ADA expert work group looked at studies in adults and concluded that using aspartame in the context of a reduced calorie diet doesn’t affect weight and may be associated with increased weight loss. This body of research was also given a grade 1.
- For years, misinformation about negative effects of aspartame has proliferated on the internet. The committee evaluated peer-reviewed research from the scientific literature on this topic and concluded: “Aspartame consumption is not associated with adverse effects in the general population”. Once again, the expert work group found that the support for this statement is grade 1.
In 2008, the ADA began this in-depth analysis of a list of questions about aspartame using its ‘evidence analysis’ approach, which systematically and rigourously evaluates relevant human studies that fall within specific, predetermined parameters.
Factors such as size and quality of each study and potential bias are taken into account. After each study is analysed by registered dieticians (RD), a separate expert group of RDs applies that research to the questions at hand. A conclusion statement is formulated for each question, and a ‘grade’ is assigned to each statement indicating the strength of the evidence supporting that conclusion.
“Given the mixed messages consumers receive about low-calorie sweeteners and weight management, the aspartame review is quite timely,” said Lisa Carlson, a Chicago-based registered dietician. “It adds meaningful, science-based information that will help registered dieticians respond to questions from consumers.”
Source: Ajinomoto North America
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