A placebo-controlled, randomised clinical trial conducted by Shim B et al at Ewha Woman’s University in Seoul, South Korea, and supported by Frutarom Health BU, Switzerland, was published in April 2014.
Go-Less, developed and marketed by Frutarom Health BU, is a proprietary blend of a water-soluble pumpkin seed extract (EFLA940) and the soy germ extract, SoyLife. Separately, both ingredients have been successfully marketed for many years. Now, combined into the proprietary blend Go-Less, they show a combined effect of the constituents from pumpkin seeds and the hormone-balancing action of soy germ isoflavones.
The study included 120 women suffering from overactive-bladder-related voiding dysfunction. The women, aged between 35 and 70 years, took 500mg of Go-Less or matching placebo tablets (60 placebo/60 test group) twice a day during a 12-week period. The average frequency of nocturia was measured, showing a notable decrease of around 30%.
After week 12, a significant decrease of the daily average frequency of urination was reported. More critically, there was a substantial decrease in the average urgency score in the Go-Less group.
The functionality of Go-Less was also confirmed by a survey on the subjective satisfaction of the participants, as conducted at the end of the trial period. More than 90% of the subjects in the Go-Less group found the product helpful and answered affirmatively when asked if they would like to continue taking the study product. This compares to about 50% in the placebo group.
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