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Pow.Bio, an AI-driven continuous fermentation company, and Bühler Group, a global provider of food and advanced materials solutions, have partnered to bring an integrated continuous precision fermentation platform to market.

The collaboration combines Pow.Bio’s continuous fermentation technology with Bühler’s engineering and deployment expertise, supported by advanced model-driven control software. The platform is designed to replace traditional batch and fed-batch fermentation methods, offering higher productivity, improved process consistency and lower unit production costs.

The solution targets companies producing fermentation-derived products – from enzymes and organic acids to functional proteins, speciality lipids and bioactive compounds – that face cost, scalability or output challenges with conventional systems. By enabling a continuous, model-driven process, the platform offers a smoother path from lab to pilot and industrial scale.

Shannon Hall, CEO and co-founder of Pow.Bio, said: “Our collaboration with Bühler sets a new benchmark for biomanufacturing: not just faster, but smarter and more robust. Clients can now capitalize on proven technology and global deployment expertise to unlock commercial-scale production with lower risk and unprecedented efficiency."

"This partnership solidifies Pow.Bio’s position at the forefront of industrial biotechnology, enabling us to deliver enduring value for our clients and the sector as a whole.”

Thierry Duvanel, Bühler’s North American director of innovation, added: “Precision fermentation has the potential to impact the food, feed, and specialty ingredients industries. Companies are already using it to produce dairy, meat and egg substitutes, alternative oils and fats and even novel pet food – and we are only at the beginning of what this technology can unlock."

"By joining forces with Pow.Bio, we take a clear step toward reducing unit production costs in biomanufacturing, combining complementary expertise to accelerate innovation and deliver a fully integrated system backed by experience, service and reliability.”

Following Pow.Bio’s 3,000 litres scale-up with Bühler’s support, both companies are now ready to onboard customers and expand adoption across the sector.